BIO.md

AI doesn't really know you.

When you ask about sleep, training, nutrition, health, or anything personal, your favourite AI tools respond only with population-level advice — what works for most people, not you.

BIO.md is the missing context that AI needs to actually understand you.

With BIO.md, AI learns how your body works, what it needs, and how to get the most out of it. Every conversation becomes a conversation tailored to your unique biology.

Average advice

How much coffee is too much?

Up to 400mg per day (about 4 cups) is generally considered safe for most adults. However, individual tolerance can vary. If you're experiencing jitteriness, anxiety, or sleep issues, consider reducing your intake.

Reply...

Advice built for you

How much coffee is too much?

Two cups max, and none after 11am. Here's why — you carry a gene variant called CYP1A2 AC, which basically means your body breaks down caffeine about half as fast as most people. That afternoon coffee? It's still buzzing around your system 8–10 hours later, quietly wrecking your sleep even if you don't feel wired. Switch to decaf or green tea after your morning window and you'll probably notice better sleep within a week.

Reply...

From raw DNA to
machine-readable biology

Your DNA contains millions of data points. We read the patterns and produce a structured file any tool can understand.

Read the full technical documentation →

📄 genome_raw_data.txtDNA export
1# rsid chromosome position genotype
2rs762551 15 75041917 AC
3rs4988235 2 136608646 CT
4rs1815739 11 66328095 CT
5rs4680 22 19951271 AG
6rs1800497 11 113400106 CT
7rs53576 3 8762685 GG
8rs6265 11 27679916 CT
9rs9939609 16 53820527 AT
10rs1801133 1 11856378 CT
11rs1800955 11 113296324 TC
12# ... ~700,000 directly genotyped variants
13# Millions more inferred via imputation
BIO.mdYour biology
1## Biological Context — BIO.md
2# Paste into AI custom instructions
3# Generated by Humankind (humans.inc)
4 
5### Archetype: SEHNNC
6 
7[Metabolic Pacing]
8caffeine_metabolism: slow (CYP1A2 AC)
9half_life: ~8-10 hours
10cutoff: before 11am
11alcohol_flush: partial sensitivity
12 
13[Physical Architecture]
14muscle_fibre: endurance-dominant (ACTN3 CT)
15training_bias: sustained effort > power
16recovery_rate: moderate
17 
18[Sensory Gain]
19processing_depth: high-gain
20light_sensitivity: elevated
21environment_note: needs low-stim for
22 deep work; overstimulates easily
23 
24[Stress Recovery]
25COMT: intermediate (Val/Met)
26dopamine_clearance: moderate
27stress_style: sustains focus under
28 pressure; needs deliberate wind-down
29 
30[Fuel Partitioning]
31FTO: AT — moderate storage tendency
32satiety: slightly blunted signalling
33strategy: protein-forward, pre-portion
34 
35# Scored from 80+ candidate variants
36# + genome-wide signal (millions of
37# imputed variants via Bayesian
38# shrinkage across 15+ GWAS traits)

Just paste it.

BIO.md works with any AI tool that supports custom instructions or persistent context. No API. No app. Just paste.

ChatGPT
Claude
Gemini
Grok

How it works

1

Upload your DNA file

Already have data from 23andMe, Ancestry, MyHeritage, or Nebula? Upload your raw data file. No file? We send you an at-home saliva collection kit.

2

We read the patterns

We analyse 80+ candidate variants directly, impute millions more, and compute genome-wide scores across 15+ traits using Bayesian shrinkage methods from population studies with hundreds of thousands of participants.

3

Get your BIO.md

You receive your structured, portable file covering all seven biological dimensions. Paste it into ChatGPT, Claude, Gemini, or Grok. Every response is now tailored to your biology.

Seven biological dimensions.
One portable file.

Each dimension maps genetic variants to practical context any AI can use.

🕯️

How fast you clear compounds

Metabolic Pacing

How quickly you break down caffeine, alcohol, and medications. Some people clear a coffee in 3 hours — others take 8.

🥾

What you're built for

Physical Architecture

Whether your muscles lean toward power or endurance, how efficiently you use oxygen, and how resilient your joints and tendons are. This is why the same training program works brilliantly for one person and does nothing for another.

📡

How you process stimuli

Sensory Gain

How sensitive you are to things like noise, light, taste, and pain. Some people thrive in chaos — others are drained by it. This comes from thousands of tiny genetic signals working together, and it explains why certain environments leave you wired while someone else barely notices.

🦉

When you function best

Circadian Pacing

Your natural clock — when you're sharpest, when you should sleep, and when your body starts producing melatonin. This comes from some of the largest genetic studies ever done and explains why forcing a morning routine works for some people and ruins others.

🪨

How you handle pressure

Stress Recovery

How quickly stress hits you and how fast your body recovers from it. These are two separate things, and your combination changes everything about how you should structure work, rest, and downtime.

🧭

What motivates you

Drive Profile

How your brain responds to rewards, novelty, and routine. Whether you're someone who thrives chasing new things or sticking to a plan — and why discipline comes naturally to some people but feels like swimming upstream for others.

🔋

How your body stores and burns energy

Fuel Partitioning

How your appetite signals work, whether your body prefers burning fat or carbs, and why some eating patterns feel effortless for you while others leave you constantly hungry. No single gene controls this — it's the combined effect of many working together, which is why generic diet advice misses the mark.

Stop following average advice.
Start following your biology.

Get your BIO.md and personalise every AI tool you use.

I have my DNA file

Upload your existing 23andMe, Ancestry, or other raw data file. Get your BIO.md within 24 hours.

I need a test kit

We send an at-home saliva collection kit. Your BIO.md arrives within 2 weeks.